The statement also reveals the Army is being drafted in and the region is to receive a six-month package of financial government support as part of the Tier 3 restrictions to be announced by Boris Johnson later on Monday amid spiralling coronavirus cases.
Negotiations are ongoing amid unhappiness over the proposed compensation package for affected workers.
Different parts of the country will be split up into “medium”, “high” or “very high” local coronavirus alert areas under the new system Boris Johnson is expected to announce on Monday.
Liverpool and Knowsley continue to be two of the worst affected areas of the country for infections, with case rates in both areas now over 600 per 100,000.
The measures could last for as long as six months, but with regular reviews that could see changes if things are improving – or if they are getting worse.
It comes after the Prime Minister held a telephone conference with Cabinet colleagues on Sunday to discuss the situation and ongoing negotiations with local leaders in the north of England.
Tier one restrictions are thought to be the baseline restrictions in place across England, including a 10pm hospitality curfew and a ban on most gatherings of more than six people.
Tier two restrictions are expected to be similar to rules currently in place in Middlesbrough and parts of the North East, where indoor mixing of households is not allowed.
Two households may be allowed to meet in a private garden, as long as the rule of six and social distancing are followed.