Staff at the Police Scotland building in Govan have tested positive for coronavirus.
Contact tracing is currently being carried out by test and protect at the Helen Street branch in Glasgow, with close contacts already being asked to self-isolate.
It is unclear how many members of staff have tested positive for the virus.
In September 2020, the Helen Street police building were also hit with a number of Covid-19 cases.
An NHS GCC spokesman said: “Test and Protect is carrying out contact tracing of Covid-19 cases linked to the Police Scotland call centre in Helen Street, Glasgow.
“To respect and maintain patient confidentiality, no further details will be released, however we can confirm that those identified so far as cases or contacts have been advised to self-isolate
“We would like to take this opportunity to remind everyone to adhere rigorously to the general advice and requirements that are set out on NHS Inform and Scottish Government websites, including immediately self-isolating and seeking a test upon developing any symptoms.”
A spokeswoman for Police Scotland added: “Police Scotland is following Scottish Government and health guidance and where cases of coronavirus are identified, we work with the local health board and adhere to Test and Protect procedures.
“We have sufficient capacity and as a national service Police Scotland can flex resources should there be a requirement to do so.”